Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239669 | 0.81 | NPC1 (0.49) | ALDH1A1HPGDTP53RAB9ANPC1 | |
| SCHEMBL7236175 | 0.79 | MAPT (0.52) | ALDH1A1HPGDTP53RAB9ANPC1 | |
| SCHEMBL7240740 | 0.74 | MAPK1 (0.50) | ALKBH1ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL1065124 | 0.74 | ALDH1A1 (0.75) | ALDH1A1HPGDTP53RAB9ANPC1 | |
| SCHEMBL120748 | 0.73 | RAB9A (0.77) | ALDH1A1HPGDTP53RAB9ANPC1 | |
| SCHEMBL12875570 | 0.72 | HPGD (0.56) | ALDH1A1HPGDRAB9ANPC1KMT2A | |
| SCHEMBL4126156 | 0.72 | POLB (0.53) | ALDH1A1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL4701633 | 0.72 | HPGD (0.50) | ALDH1A1HPGDTP53RAB9ANPC1 | |
| SCHEMBL7169969 | 0.71 | GAA (0.52) | ALDH1A1HPGDTP53RAB9ANPC1 | |
| SCHEMBL7230301 | 0.71 | RAB9A (0.51) | ALDH1A1HPGDTP53RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552018-B1 | As antitumor agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-6169086-B1 | AN ANTITUMOR AGENT FOR TREATING TUMOR RESISTANT TO 5-FLUOROURACIL TYPE DRUGS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| EP-1022270-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-07-26 | — | — | EP | disclosed |