Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 5/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870562 | 0.81 | CA12 (0.44) | HTR6KMT2AHDAC8RAB9A | |
| SCHEMBL8836613 | 0.80 | CA1 (0.36) | NTSR1KMT2AHDAC8ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8836099 | 0.80 | CA12 (0.43) | HTR6KMT2AHDAC8RAB9A | |
| Acetic Acid SCHEMBL8835962 | 0.79 | NOTUM (0.45) | NTSR1KMT2AALDH1A1RAB9A | |
| SCHEMBL8836401 | 0.79 | OXER1 (0.44) | HDAC8 | |
| SCHEMBL8836009 | 0.78 | LTA4H (0.53) | KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL8835933 | 0.76 | HTR6 (0.44) | HTR6AOC3KMT2AALDH1A1 | |
| SCHEMBL8836533 | 0.76 | MTNR1A (0.52) | HTR6HDAC8ALDH1A1SMN1; SMN2 | |
| SCHEMBL8836240 | 0.76 | MTNR1A (0.52) | HTR6HDAC8ALDH1A1SMN1; SMN2 | |
| SCHEMBL8836539 | 0.75 | TP53 (0.43) | KMT2ANPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220340-A1 | Aryl and heteroaryl compounds as antibacterial and antifungal agents | GLAXOSMITHKLINE LLC | 2003-11-27 | — | — | US | claimed |
| US-20030220340-A1 | Aryl and heteroaryl compounds as antibacterial and antifungal agents | GLAXOSMITHKLINE LLC | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220340-A1 | Aryl and heteroaryl compounds as antibacterial and antifungal agents | AADAC, ERG28, LSS | NTSR1 3154/4885HTR6 2937/4885AOC3 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.