Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8131220 | 0.95 | PIK3CD (0.34) | SPHK1SPHK2PIK3CDALDH1A1USP2 | |
| SCHEMBL10458440 | 0.95 | PIK3CD (0.34) | SPHK1SPHK2PIK3CDALDH1A1USP2 | |
| SCHEMBL11858528 | 0.89 | SPHK1 (0.42) | SPHK1SPHK2ALDH1A1USP2HTT | |
| SCHEMBL10119365 | 0.86 | SPHK1 (0.44) | SPHK1SPHK2ALDH1A1USP2HTT | |
| SCHEMBL31086433 | 0.86 | SPHK1 (0.44) | SPHK1SPHK2ALDH1A1USP2HTT | |
| SCHEMBL1298691 | 0.83 | — | — | |
| SCHEMBL3962044 | 0.83 | SPHK1 (0.38) | SPHK1SPHK2ALDH1A1USP2HTT | |
| SCHEMBL12396063 | 0.83 | TDP1 (0.37) | LPAR1LPAR3 | |
| SCHEMBL18387283 | 0.82 | ALDH1A1 (0.38) | SPHK1ALDH1A1USP2HTTPRKD3 | |
| SCHEMBL6535744 | 0.81 | PIK3CD (0.36) | PIK3CDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017075351-A1 | POLYURETHANE BINDER CONTAINING ALCOHOL SOLVENT | ASK CHEMICALS, L.P. (US) | 2017-05-04 | — | — | WO | disclosed |
| US-9320685-B2 | Dental compositions comprising ethylenically unsaturated addition-fragmentation agent | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-04-26 | — | — | US | disclosed |
| US-9295617-B2 | Dental composition, method of producing and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-03-29 | — | — | US | disclosed |
| US-20150238389-A1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2015-08-27 | — | — | US | disclosed |
| US-9056043-B2 | Dental compositions comprising ethylenically unsaturated addition-fragmentation agent | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-06-16 | — | — | US | disclosed |
| US-9012531-B2 | Dental compositions comprising mixture of isocyanurate monomer and tricyclodecane monomer | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-04-21 | — | — | US | disclosed |
| EP-2598550-B1 | BINDER SYSTEM BASED ON POLYURETHANE FOR PRODUCING CORES AND CASTING MOLDS USING CYCLIC FORMALDEHYDES, MOLDING MATERIAL MIXTURE, AND METHOD | ASK CHEMICALS GMBH (DE) | 2014-12-31 | — | — | EP | disclosed |
| US-20140300031-A1 | BINDER SYSTEM BASED ON POLYURETHANE FOR PRODUCING CORES AND CASTING MOLDS USING CYCLIC FORMALS, MOLDING MATERIAL MIXTURE, AND METHOD | ASK CHEMICALS GMBH (DE) | 2014-10-09 | — | — | US | disclosed |
| US-20140220512-A1 | DENTAL COMPOSITIONS COMPRISING MIXTURE OF ISOCYANURATE MONOMER AND TRICYCLODECANE MONOMER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-08-07 | — | — | US | disclosed |
| US-8710113-B2 | Dental composition, kit of parts and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-11-14 | — | — | US | disclosed |
| EP-2598550-A1 | BINDER SYSTEM BASED ON POLYURETHANE FOR PRODUCING CORES AND CASTING MOLDS USING CYCLIC FORMALDEHYDES, MOLDING MATERIAL MIXTURE, AND METHOD | ASK Chemicals GmbH (DE) | 2013-06-05 | — | — | EP | disclosed |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| WO-2012025084-A1 | BINDER SYSTEM BASED ON POLYURETHANE FOR PRODUCING CORES AND CASTING MOLDS USING CYCLIC FORMALDEHYDES, MOLDING MATERIAL MIXTURE, AND METHOD | ASK CHEMICALS GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |
| US-4172068-A | POLYOL, POLYISOCYANATE; ACETAL OR KETAL AS SOLVENT | INTERNATIONAL MINERALS & CHEMICAL CORPORATION (US) | 1979-10-23 | — | — | US | disclosed |
| US-4116916-A | BINDER, PHENOL-FORMALDEHYDE RESIN, POLYISOCYANATE, SOLVENT | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1978-09-26 | — | — | US | disclosed |
| US-4051092-A | CURABLE RESIN, POLYISOCYANATE | INTERNATIONAL MINERALS & CHEMICAL CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | PAM, PTMS, ACR | SPHK1 4868/4885SPHK2 4840/4885PIK3CD 2998/4885 |
| US-20140220512-A1 | DENTAL COMPOSITIONS COMPRISING MIXTURE OF ISOCYANURATE MONOMER AND TRICYCLODECANE MONOMER | INTS9, INTS6, ERCC1 | SPHK1 4859/4885SPHK2 4822/4885PIK3CD 2402/4885 |
| US-20150238389-A1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | NR4A1, RXRG, RXRA | SPHK1 4479/4885SPHK2 4412/4885PIK3CD 3449/4885 |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | KIT, KDM5C, PHAX | SPHK1 4707/4885SPHK2 4643/4885PIK3CD 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.