Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 3/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | ILK | Q13418 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 3/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3740850 | 0.73 | AKT2 (0.70) | AKT2AKT1ILKMAPK1KCNH2 | |
| Hydrochloric Acid SCHEMBL28973063 | 0.71 | AKT2 (0.67) | AKT2AKT1ILKMAPK1KCNH2 | |
| SCHEMBL18955827 | 0.71 | AKT2 (0.45) | AKT2AKT1ILKMAPK1KCNH2 | |
| SCHEMBL7240451 | 0.69 | ATM (0.33) | — | |
| SCHEMBL443517 | 0.67 | LMNA (0.43) | MAPT | |
| SCHEMBL70645 | 0.67 | ALDH1A1 (0.42) | MAPT | |
| SCHEMBL17625974 | 0.67 | PIK3CD (0.43) | MAPK1MAPT | |
| SCHEMBL1667738 | 0.67 | — | — | |
| SCHEMBL29533228 | 0.67 | AKT2 (0.61) | AKT2AKT1ILKMAPK1KCNH2 | |
| SCHEMBL16432987 | 0.67 | AKT2 (0.76) | AKT2AKT1ILKPIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199046-A1 | Processes and intermediates useful in preparing beta3-adrenergic receptor agonists | CHAMBERS ROBERT J (US) | 2003-10-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199046-A1 | Processes and intermediates useful in preparing beta3-adrenergic receptor agonists | ADRB3, ADRB1, ADRB2 | AKT2 1749/4885AKT1 1227/4885ILK 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.