Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540279 | 0.96 | RAB9A (0.47) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL6250258 | 0.86 | NPC1 (0.49) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL7325044 | 0.84 | ALDH1A2 (0.35) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL443517 | 0.82 | LMNA (0.43) | KMT2ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL1435684 | 0.80 | NPC1 (0.61) | KMT2ARAB9AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL17626009 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL10515566 | 0.78 | LTA4H (0.46) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL1916309 | 0.78 | KMT2A (0.47) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL468044 | 0.78 | RAB9A (0.41) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL1387640 | 0.78 | CYP19A1 (0.50) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027085-A | Organic electroluminescent compound and application thereof | 宁波卢米蓝新材料有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-113929696-B | Acyl thiourea psoralen derivatives, and preparation method and application thereof | 南开大学 | 2024-05-14 | — | — | CN | claimed |
| US-20230390259-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2023-12-07 | — | — | US | claimed |
| EP-4247797-A1 | 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-09-27 | — | — | EP | claimed |
| US-20230286927-A1 | 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2023-09-14 | — | — | US | claimed |
| CN-116438176-A | 2-phenylbenzotriazol-5-amine derivatives for the treatment and prevention of Hepatitis B Virus (HBV) infection | 豪夫迈·罗氏有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-114835736-A | Compound, display panel and display device | 武汉天马微电子有限公司 | 2022-08-02 | — | — | CN | claimed |
| WO-2022106588-A1 | 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2022-05-27 | — | — | WO | claimed |
| US-20220153713-A1 | HYDRAZONE AMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING ALOPECIA | SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2022-05-19 | — | — | US | claimed |
| US-20220153688-A1 | HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS | SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2022-05-19 | — | — | US | claimed |
| US-4762921-A | 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives | PFIZER INC. (US) | 1988-08-09 | — | — | US | claimed |
| WO-1988000183-A1 | S-TRIFLUOROBUTENYL DERIVATIVES AND PESTICIDAL USES | FMC CORPORATION (US) | 1988-01-14 | — | — | WO | claimed |
| CN-87104606-A | S-trifluoro butenyl derivative and pesticidal use | — | 1988-01-13 | — | — | CN | claimed |
| US-4675186-A | 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives | PFIZER INC. (US) | 1987-06-23 | — | — | US | claimed |
| EP-0201221-A1 | 6-(1-acyl-1-hydroxy methyl) penicillanic acid derivatives | PFIZER INC. (US) | 1986-11-12 | — | — | EP | claimed |
| EP-0061094-B1 | ELECTROPHOTOGRAPHIC RECORDING MATERIAL | BASF Aktiengesellschaft (DE) | 1985-10-02 | — | — | EP | claimed |
| US-4481272-A | ISOINDOLE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1984-11-06 | — | — | US | claimed |
| EP-0061094-A1 | Electrophotographic recording material | BASF Aktiengesellschaft (DE) | 1982-09-29 | — | — | EP | claimed |
| EP-0006368-B1 | 4-PHENYL-THIAZOLYL-2-OXAMATE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF ASTHMA | PIERRE FABRE S.A. (FR) | 1981-11-18 | — | — | EP | claimed |
| US-4294581-A | ANTHRAQUINONE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230390259-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | PLPBP, PDXK, PIR | ALDH1A1 2259/4885KMT2A 2767/4885RAB9A 2967/4885 |
| US-20220153688-A1 | HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS | SOST, HDAC5, PTH1R | ALDH1A1 644/4885KMT2A 796/4885RAB9A 607/4885 |
| US-20220153713-A1 | HYDRAZONE AMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING ALOPECIA | FH, HDGF, HRH4 | ALDH1A1 652/4885KMT2A 1019/4885RAB9A 4485/4885 |
| US-20230286927-A1 | 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION | HAVCR2, NR1H4, SLC10A1 | ALDH1A1 1080/4885KMT2A 473/4885RAB9A 1884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.