Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607654 | 0.80 | HRH2 (0.38) | KDM4EALDH1A1HRH3HRH2HRH1 | |
| SCHEMBL7246374 | 0.78 | PIK3CD (0.47) | CYP1A2TDP1PAOXPIK3CDDRD3 | |
| SCHEMBL4498845 | 0.78 | DRD3 (0.45) | CYP1A2TDP1PIK3CDDRD3KDM4E | |
| SCHEMBL1719282 | 0.75 | ALDH1A1 (0.35) | PAOXKDM4EALDH1A1USP2POLB | |
| SCHEMBL4498843 | 0.73 | PIK3CD (0.51) | CYP1A2TDP1PIK3CDDRD3KDM4E | |
| SCHEMBL21659718 | 0.73 | HRH3 (0.44) | PIK3CDDRD3KDM4EALDH1A1USP2 | |
| SCHEMBL6043046 | 0.72 | DRD3 (0.53) | CYP1A2TDP1PIK3CDDRD3KDM4E | |
| SCHEMBL2573857 | 0.71 | ALDH1A1 (0.40) | CYP1A2TDP1KDM4EALDH1A1USP2 | |
| SCHEMBL5492084 | 0.70 | CNR2 (0.35) | CYP1A2KDM4EALDH1A1HRH3POLB | |
| SCHEMBL297316 | 0.69 | CYP1A2 (0.52) | CYP1A2TDP1PAOXPIK3CDDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186966-A1 | Amide derivatives | ASTRAZENECA AB | 2003-10-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186966-A1 | Amide derivatives | IL6, IL6ST, IFNG | CYP1A2 244/4885TDP1 3741/4885PAOX 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.