Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ATP4A | P20648 | 1/20 | 0.35 |
| ▸ | ATP4B | P51164 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511848 | 0.90 | KDM4E (0.39) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL16426339 | 0.77 | CYP24A1 (0.43) | KDM4EALDH1A1MMP9ATP4AATP4B | |
| SCHEMBL10192245 | 0.77 | ATP4A (0.39) | ALDH1A1ATP4AATP4BSLC6A2SLC6A4 | |
| SCHEMBL16555972 | 0.77 | ALDH1A1 (0.45) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL17787935 | 0.74 | ATP4A (0.37) | KDM4EATP4AATP4BSLC6A2SLC6A4 | |
| SCHEMBL22704634 | 0.73 | SLC6A2 (0.36) | ALDH1A1ATP4AATP4BSLC6A2SLC6A4 | |
| SCHEMBL24465605 | 0.73 | CYP19A1 (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31295219 | 0.72 | KDM4E (0.52) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL14587709 | 0.72 | SLC6A2 (0.36) | ALDH1A1ATP4AATP4BSLC6A2SLC6A4 | |
| Sulfuric Acid SCHEMBL16340543 | 0.71 | ALDH1A1 (0.38) | ALDH1A1TSHRPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3026049-B1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | DONG A ST CO LTD (KR) | 2021-09-22 | — | — | EP | disclosed |
| US-9771348-B2 | Method for preparing benzamide derivative, novel intermediate used in preparation of benzamide, and method for preparing novel intermediate | DONG-A ST CO., LTD (KR) | 2017-09-26 | — | — | US | disclosed |
| US-9771348-B2 | Method for preparing benzamide derivative, novel intermediate used in preparation of benzamide, and method for preparing novel intermediate | DONG-A ST CO., LTD (KR) | 2017-09-26 | — | — | US | disclosed |
| US-20160185751-A1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | DONG-A ST CO., LTD (KR) | 2016-06-30 | — | — | US | disclosed |
| US-20160185751-A1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | DONG-A ST CO., LTD (KR) | 2016-06-30 | — | — | US | disclosed |
| EP-2560955-B1 | NOVEL BENZAMIDE DERIVATIVES | DONG A PHARM CO LTD (KR) | 2016-06-29 | — | — | EP | disclosed |
| EP-3026049-A1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | Dong-A ST Co., Ltd. (KR) | 2016-06-01 | — | — | EP | disclosed |
| EP-3026049-A1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | Dong-A ST Co., Ltd. (KR) | 2016-06-01 | — | — | EP | disclosed |
| CN-105636946-A | Method for preparing benzamide derivative, novel intermediate used in preparation of benzamide, and method for preparing novel intermediate | DONG A ST CO LTD | 2016-06-01 | — | — | CN | disclosed |
| US-9221790-B2 | Benzamide derivatives | DONG-A PHARM. CO., LTD. (KR) | 2015-12-29 | — | — | US | disclosed |
| WO-2015012515-A1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | 동아에스티 주식회사 (KR) | 2015-01-29 | — | — | WO | disclosed |
| US-20130085160-A1 | NOVEL BENZAMIDE DERIVATIVES | DONG-A PHARM. CO., LTD. (KR) | 2013-04-04 | — | — | US | disclosed |
| EP-2560955-A2 | NOVEL BENZAMIDE DERIVATIVES | Dong-A Pharm.Co., Ltd. (KR) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011132901-A2 | NOVEL BENZAMIDE DERIVATIVES | DONG-A PHARM.CO., LTD. (KR) | 2011-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185751-A1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | HTR4, HTR5A, HTR2B | KDM4E 719/4885USP2 3109/4885ALDH1A1 1079/4885 |
| US-20130085160-A1 | NOVEL BENZAMIDE DERIVATIVES | HTR4, GPR4, HTR5A | KDM4E 1161/4885USP2 2941/4885ALDH1A1 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.