Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.42 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7246252 | 0.85 | ALDH1A1 (0.61) | MAPTALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL395368 | 0.85 | ALDH1A1 (0.66) | MAPTALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL9018938 | 0.85 | ALDH1A1 (0.61) | MAPTALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL11645241 | 0.81 | MAPT (0.60) | MAPTALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL6562023 | 0.81 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL486125 | 0.80 | MAPT (0.73) | MAPTALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL8418696 | 0.80 | MAPT (0.59) | MAPTALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL4033095 | 0.80 | MAPT (0.59) | MAPTALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL27752106 | 0.79 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL4033097 | 0.79 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4EKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670387-B1 | Thrombocytopenia; hydroxy-1-azo-naphthalene derivatives; 3-hydroxy-4-((2-hydroxy-1-naphthalenyl)azo-)-1-naphthalenesul fonic acid; promoters of thrombopoiesis and megakaryocytopoi esis; enhancing platelet production; agonizing TPO receptor | SMITHKLINE BEECHAM CORPORATION | 2003-12-30 | — | — | US | disclosed |
| EP-1156804-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1156804-A1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000035446-A1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-06-22 | — | — | WO | disclosed |
| US-4086223-A | Asymmetrical 1:2-chromium complex azo dyestuffs | CIBA-GEIGY AG (CH) | 1978-04-25 | — | — | US | disclosed |