SCHEMBL9018938

SCHEMBL9018938

Cc1cc(=O)n(-c2ccc(S(=O)(=O)Cl)cc2)[nH]1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.61
MAPT P10636 7/20 0.61
KMT2A Q03164 6/20 0.61
KDM4E B2RXH2 5/20 0.61
HTT P42858 4/20 0.61
MEN1 O00255 3/20 0.61
GAA P10253 2/20 0.61
LMNA P02545 4/20 0.58
RECQL P46063 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.56
TDP1 Q9NUW8 2/20 0.56
ALPL P05186 1/20 0.42
ALKBH3 Q96Q83 1/20 0.41
KDM5A P29375 1/20 0.40
KDM2B Q8NHM5 1/20 0.40
KDM4C Q9H3R0 1/20 0.40
ALKBH5 Q6P6C2 6/20 0.39
POLB P06746 1/20 0.37
BLM P54132 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7247608 0.85 MAPT (0.63) ALDH1A1MAPTKMT2AKDM4EHTT
SCHEMBL395368 0.84 ALDH1A1 (0.66) ALDH1A1MAPTKMT2AKDM4EHTT
SCHEMBL7246252 0.84 ALDH1A1 (0.61) ALDH1A1MAPTKMT2AKDM4EHTT
SCHEMBL11645241 0.80 MAPT (0.60) ALDH1A1MAPTKMT2AKDM4EHTT
SCHEMBL6562023 0.80 ALDH1A1 (0.56) ALDH1A1MAPTKMT2AKDM4EHTT
SCHEMBL486340 0.80 ALDH1A1 (0.69) ALDH1A1MAPTKMT2AKDM4EHTT
SCHEMBL486125 0.79 MAPT (0.73) ALDH1A1MAPTKMT2AKDM4EHTT
SCHEMBL4033095 0.79 MAPT (0.59) ALDH1A1MAPTKMT2AKDM4EHTT
SCHEMBL8418696 0.79 MAPT (0.59) ALDH1A1MAPTKMT2AKDM4EHTT
SCHEMBL27752106 0.78 ALDH1A1 (0.57) ALDH1A1MAPTKMT2AKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0445926-B1 Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation MILLIKEN RES CORP (US) 1996-08-21 EP disclosed
US-5240464-A Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation MILLIKEN RESEARCH CORPORATION (US) 1993-08-31 US disclosed