SCHEMBL6562023

SCHEMBL6562023

C=CS(=O)(=O)c1ccc(-n2[nH]c(C)cc2=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
MAPT P10636 7/20 0.56
KDM4E B2RXH2 4/20 0.56
KMT2A Q03164 4/20 0.56
HTT P42858 3/20 0.56
GAA P10253 2/20 0.56
MEN1 O00255 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
TDP1 Q9NUW8 1/20 0.56
LMNA P02545 3/20 0.54
RECQL P46063 1/20 0.54
NPC1 O15118 1/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
XBP1 P17861 1/20 0.40
MAPK1 P28482 1/20 0.40
RAB9A P51151 1/20 0.40
MDM2 Q00987 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM5A P29375 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL395368 0.83 ALDH1A1 (0.66) ALDH1A1MAPTKDM4EKMT2AHTT
SCHEMBL7247608 0.81 MAPT (0.63) ALDH1A1MAPTKDM4EKMT2AHTT
SCHEMBL9018938 0.80 ALDH1A1 (0.61) ALDH1A1MAPTKDM4EKMT2AHTT
SCHEMBL7246252 0.80 ALDH1A1 (0.61) ALDH1A1MAPTKDM4EKMT2AHTT
SCHEMBL9176966 0.80 ALKBH5 (0.61) ALDH1A1MAPTKDM4EKMT2AHTT
SCHEMBL8418696 0.78 MAPT (0.59) ALDH1A1MAPTKDM4EKMT2AHTT
SCHEMBL10487415 0.77 NPC1 (0.43) ALDH1A1MAPTHTTSMN1; SMN2TDP1
SCHEMBL10654204 0.77 ALDH1A1 (0.60) ALDH1A1MAPTKDM4EKMT2AHTT
SCHEMBL11645241 0.77 MAPT (0.60) ALDH1A1MAPTKDM4EKMT2AHTT
SCHEMBL486125 0.76 MAPT (0.73) ALDH1A1MAPTKDM4EKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1055710-B1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2004-08-11 EP disclosed
US-6444794-B1 COMPLEXING WITH SUBSTRATE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-09-03 US disclosed
EP-1055710-A1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-11-29 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 US disclosed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 EP disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 EP disclosed
EP-0629667-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AG (DE) 1998-02-25 EP disclosed
EP-0548795-B1 Water-soluble reactive dyes, their manufacture and their use HOECHST AG (DE) 1997-07-09 EP disclosed
US-5243034-A Disazo dyestuffs having a triazine moiety and a fiberreactive group of vinylsulfone series HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-07 US disclosed
US-5225544-A FIBER REACTIVE DYES WHICH CONTAIN A CYANOAMINOTRIAZINYL GROUP AND ONE OR TWO GROUPS OF THE VINYL SULFONE SERIES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0548795-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0542214-A2 Water-soluble fibre-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP disclosed
US-5138041-A Water-soluble fiber-reactive monoazo and disazo dyestuffs having a s-triazinylamino group and three fiber-reactive groups of the vinylsulfone series HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-11 US disclosed
EP-0377166-A1 Water-soluble, fibre-reactive dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-11 EP disclosed
EP-0374758-A1 Water soluble dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP disclosed
US-4808193-A Process for dyeing hydroxy-containing fiber material with water-soluble dis-azo reactive dye compound HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-28 US disclosed
US-4762916-A CELLULOSE FABRICS HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed