SCHEMBL7246252

SCHEMBL7246252

Cc1cc(=O)n(-c2ccc(S(N)(=O)=O)cc2)[nH]1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
MAPT P10636 4/20 0.61
KDM4E B2RXH2 4/20 0.61
GAA P10253 2/20 0.61
HTT P42858 2/20 0.61
KMT2A Q03164 2/20 0.61
MEN1 O00255 1/20 0.61
LMNA P02545 2/20 0.58
RECQL P46063 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
ALOX5 P09917 2/20 0.50
PTGS2 P35354 2/20 0.50
CA12 O43570 12/20 0.47
CA1 P00915 12/20 0.47
CA2 P00918 12/20 0.47
CA9 Q16790 12/20 0.47
CA3 P07451 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7247608 0.85 MAPT (0.63) ALDH1A1MAPTKDM4EGAAHTT
SCHEMBL9018938 0.84 ALDH1A1 (0.61) ALDH1A1MAPTKDM4EGAAHTT
SCHEMBL395368 0.84 ALDH1A1 (0.66) ALDH1A1MAPTKDM4EGAAHTT
SCHEMBL9789614 0.83 CA1 (0.49) ALDH1A1MAPTKDM4EGAAHTT
SCHEMBL11645241 0.80 MAPT (0.60) ALDH1A1MAPTKDM4EGAAHTT
SCHEMBL6562023 0.80 ALDH1A1 (0.56) ALDH1A1MAPTKDM4EGAAHTT
SCHEMBL8166341 0.80 ALDH1A1 (0.69) ALDH1A1MAPTKDM4EGAAHTT
SCHEMBL486125 0.79 MAPT (0.73) ALDH1A1MAPTKDM4EGAAHTT
SCHEMBL4033095 0.79 MAPT (0.59) ALDH1A1MAPTKDM4EGAAHTT
SCHEMBL8418696 0.79 MAPT (0.59) ALDH1A1MAPTKDM4EGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4474695-A Complex dye mixture containing at least two cobalt 1:2 complexes of azo dyes BASF AKTIENGESELLSCHAFT (DE) 1984-10-02 US claimed
US-6670387-B1 Thrombocytopenia; hydroxy-1-azo-naphthalene derivatives; 3-hydroxy-4-((2-hydroxy-1-naphthalenyl)azo-)-1-naphthalenesul fonic acid; promoters of thrombopoiesis and megakaryocytopoi esis; enhancing platelet production; agonizing TPO receptor SMITHKLINE BEECHAM CORPORATION 2003-12-30 US disclosed
EP-0181585-B1 FIBRE-REACTIVE MONOAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-04 EP disclosed
EP-0181585-A2 Fibre-reactive monoazo compounds, process for their preparation and their dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1986-05-21 EP disclosed
EP-0072557-B1 WATER-SOLUBLE AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-03-20 EP disclosed
EP-0071985-B1 WATER-SOLUBLE MONO-AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-03-20 EP disclosed
EP-0055808-B1 MIXTURES OF METAL-COMPLEX DYESTUFFS BASF Aktiengesellschaft (DE) 1985-01-16 EP disclosed
US-4474695-A Complex dye mixture containing at least two cobalt 1:2 complexes of azo dyes BASF AKTIENGESELLSCHAFT (DE) 1984-10-02 US disclosed
EP-0055808-A2 Mixtures of metal-complex dyestuffs BASF Aktiengesellschaft (DE) 1982-07-14 EP disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed