Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676262 | 0.89 | PTGER4 (0.41) | MEN1KMT2ANAMPTCA1CA2 | |
| SCHEMBL6674728 | 0.89 | MEN1 (0.36) | MEN1KMT2AATMCYP17A1 | |
| SCHEMBL6675282 | 0.88 | NAMPT (0.40) | MEN1KMT2ANAMPTCA1CA2 | |
| Hydrochloric Acid SCHEMBL7242320 | 0.88 | MEN1 (0.36) | MEN1KMT2AATMCYP17A1 | |
| SCHEMBL6681999 | 0.87 | MAPT (0.45) | MEN1KMT2AATMNAMPTCA1 | |
| SCHEMBL6676115 | 0.83 | NAMPT (0.53) | KMT2ANAMPTCA1CA2CYP17A1 | |
| SCHEMBL7248116 | 0.83 | CA1 (0.43) | MEN1KMT2AATMNAMPTCA1 | |
| SCHEMBL6681072 | 0.80 | NQO2 (0.40) | MEN1KMT2ANAMPTCA1CA2 | |
| SCHEMBL6675304 | 0.79 | MTNR1A (0.41) | NQO2 | |
| SCHEMBL27478756 | 0.79 | MEN1 (0.50) | MEN1KMT2AATMNAMPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |