Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7242320 | 0.99 | MEN1 (0.36) | MEN1KMT2AATMPOLBCTDSP1 | |
| SCHEMBL7248121 | 0.89 | MEN1 (0.41) | MEN1KMT2AATMCYP17A1 | |
| SCHEMBL6676182 | 0.79 | CYP17A1 (0.39) | MEN1KMT2AATMPOLBCTDSP1 | |
| Hydrochloric Acid SCHEMBL7242318 | 0.78 | CYP17A1 (0.38) | MEN1KMT2AATMPOLBCTDSP1 | |
| Hydrochloric Acid SCHEMBL6675309 | 0.78 | CYP17A1 (0.38) | MEN1KMT2AATMPOLBCTDSP1 | |
| SCHEMBL6676262 | 0.77 | PTGER4 (0.41) | MEN1KMT2APOLBTDP1 | |
| SCHEMBL6675282 | 0.76 | NAMPT (0.40) | MEN1KMT2ATDP1 | |
| SCHEMBL6681999 | 0.76 | MAPT (0.45) | MEN1KMT2AATMPOLB | |
| Hydrochloric Acid SCHEMBL6675307 | 0.72 | ACHE (0.35) | MEN1KMT2AATMMAPK14PDK1 | |
| SCHEMBL6674730 | 0.71 | ACHE (0.34) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |