Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 7/20 | 0.43 |
| ▸ | HRH1 | P35367 | 7/20 | 0.43 |
| ▸ | CCR6 | P51684 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095214 | 0.85 | GRIN2B (0.52) | HRH2HRH1CCR6GRIN1GRIN2B | |
| SCHEMBL7246408 | 0.85 | HRH2 (0.41) | HRH2HRH1CCR6GRIN1GRIN2B | |
| SCHEMBL7251183 | 0.84 | NPC1 (0.42) | HRH2HRH1HTTNPSR1ALDH1A1 | |
| SCHEMBL7242827 | 0.82 | CCR6 (0.44) | HRH2HRH1CCR6GRIN2BMEN1 | |
| SCHEMBL7246880 | 0.82 | HRH2 (0.37) | HRH2HRH1MEN1HRH3 | |
| SCHEMBL7245472 | 0.80 | KDM1A (0.37) | HRH2HRH1HRH3 | |
| SCHEMBL7249987 | 0.80 | L3MBTL1 (0.47) | MEN1ALDH1A1KMT2A | |
| SCHEMBL2962889 | 0.79 | GRIN2B (0.45) | HRH2HRH1GRIN1GRIN2BMEN1 | |
| SCHEMBL7243888 | 0.79 | HTR7 (0.40) | HRH2HRH1MEN1HRH3 | |
| SCHEMBL7248462 | 0.79 | HRH3 (0.39) | HRH2HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096993-A1 | Stabilizer mixture | CIBA SPECIALTY CHEMICALS CORP. | 2003-05-22 | — | — | US | disclosed |
| US-6559162-B2 | Electrophysiological activity | ASTRAZENECA AB (SE) | 2003-05-06 | — | — | US | disclosed |
| US-20020137766-A1 | Azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096993-A1 | Stabilizer mixture | GSR, GLRA1, GLRA2 | HRH2 381/4885HRH1 661/4885CCR6 2031/4885 |
| US-20020137766-A1 | Azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias | KCNH1, KCNH2, KCNH3 | HRH2 321/4885HRH1 367/4885CCR6 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.