SCHEMBL724992

SCHEMBL724992

CC(=O)C(C/C=C(\C)CCC=C(C)C)C/C=C(\C)CCC=C(C)C

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FNTA P49354 4/20 0.65
FNTB P49356 4/20 0.65
KMT2A Q03164 3/20 0.56
ALOX15 P16050 3/20 0.52
MEN1 O00255 2/20 0.52
CYP3A4 P08684 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ATM Q13315 1/20 0.52
ALDH1A1 P00352 3/20 0.52
MAPT P10636 2/20 0.50
POLB P06746 1/20 0.50
UGT1A1 P22309 1/20 0.50
SQLE Q14534 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL940703 1.00 FNTA (0.65) FNTAFNTBKMT2AALOX15MEN1
SCHEMBL15639480 0.98 FNTA (0.68) FNTAFNTBKMT2AALOX15MEN1
SCHEMBL11652143 0.91 FNTA (0.59) FNTAFNTBKMT2AALOX15MEN1
SCHEMBL30368947 0.89 FNTA (0.62) FNTAFNTBKMT2AALOX15MEN1
SCHEMBL30368929 0.89 FNTA (0.62) FNTAFNTBKMT2AALOX15MEN1
SCHEMBL29004811 0.89 FNTA (0.62) FNTAFNTBKMT2AALOX15MEN1
SCHEMBL28442015 0.88 FNTA (0.56) FNTAFNTBKMT2AALOX15MEN1
SCHEMBL1395164 0.86 FNTA (0.73) FNTAFNTBKMT2AALOX15MEN1
SCHEMBL14815528 0.86 FNTA (0.58) FNTAFNTBKMT2AALOX15MEN1
SCHEMBL8619861 0.85 FNTA (0.77) FNTAFNTBKMT2AALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3445384-B1 COMPOSITION FOR TREATING DIASTOLIC DYSFUNCTION STICHTING VUMC (NL) 2023-07-12 EP claimed
US-11504415-B2 Treatment of heart failure with preserved ejection fraction STICHTING VUMC (NL) 2022-11-22 US claimed
EP-2259844-A1 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES Vicus Therapeutics SPE 1, LLC (US) 2010-12-15 EP claimed
WO-2009111648-A1 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES VICUS THERAPEUTICS, LLC (US) 2009-09-11 WO claimed
US-20080089950-A1 Methods and compositions for modulating the immune system and uses thereof CHEN LAN B 2008-04-17 US claimed
EP-1563849-A2 Methods and compositions for modulating the immune system and uses thereof DANA-FARBER CANCER INSTITUTE (US) 2005-08-17 EP claimed
EP-1455775-A2 METHODS AND COMPOSITIONS FOR MODULATING THE IMMUNE SYSTEM AND USES THEREOF DANA-FARBER CANCER INSTITUTE (US) 2004-09-15 EP claimed
US-20040022869-A1 Methods and compositions for modulating the immune system and uses thereof DANA-FARBER CANCER INSTITUTE, INC. 2004-02-05 US claimed
WO-2003047524-A2 METHODS AND COMPOSITIONS FOR MODULATING THE IMMUNE SYSTEM AND USES THEREOF DANA-FARBER CANCER INSTITUTE (US) 2003-06-12 WO claimed
JP-7215873-A None JP disclosed
JP-7309710-A None JP disclosed
US-12600969-B2 Expression control using a regulatable intron AskBio Inc. (US) 2026-04-14 US disclosed
US-12576076-B2 Use of HSP70 as a regulator of enzymatic activity Zevra Denmark A/S (DK) 2026-03-17 US disclosed
US-20250262152-A1 DEVICES, SYSTEMS, KITS, AND METHODS FOR DRUG DELIVERY TO THE SPINAL CORD OHIO STATE INNOVATION FOUNDATION 2025-08-21 US disclosed
EP-1289489-A2 TOPICAL AGENT FOR DERMATOLOGICAL USE CONTAINING 4-HYDROXYPHENYL-ALPHA-D-GLUCOPYRANOSIDE PENTAPHARM Ltd. (CH) 2003-03-12 EP disclosed
CN-1348434-A Preparation of gamma, delta-unsaturated ketones by carroll reaction BASF AG (DE) 2002-05-08 CN disclosed
WO-2001091715-A2 TOPICAL AGENT FOR DERMATOLOGICAL USE CONTAINING 4-HYDROXYPHENYL-ALPHA-D-GLUCOPYRANOSIDE PENTAPHARM LTD. (CH) 2001-12-06 WO disclosed
JP-H07309710-A EXTERNAL BASE EISAI CO LTD 1995-11-28 JP disclosed
JP-H07215873-A CARDIOTONIC OTSUKA PHARMACEUT CO LTD 1995-08-15 JP disclosed
US-4116955-A META-CYCLOPHANE AND A TRANS-TERPENOID, SEPARATION OF ISOMERS TEIJIN LIMITED (JP) 1978-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600969-B2 Expression control using a regulatable intron XBP1, ATF4, HSPA5 FNTA 979/4885FNTB 628/4885KMT2A 4762/4885
US-12576076-B2 Use of HSP70 as a regulator of enzymatic activity HSPB1, HSPA1B, HSPD1 FNTA 2571/4885FNTB 693/4885KMT2A 4482/4885
US-20080089950-A1 Methods and compositions for modulating the immune system and uses thereof ICOS, MALT1, LTA FNTA 2402/4885FNTB 4778/4885KMT2A 1874/4885
US-20040022869-A1 Methods and compositions for modulating the immune system and uses thereof ICOS, MALT1, LTA FNTA 2402/4885FNTB 4778/4885KMT2A 1874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.