Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28642472 | 0.82 | HTR2A (0.59) | KDM4EALDH1A1MAPTHTR2AHTR1A | |
| SCHEMBL597663 | 0.79 | GPR84 (0.51) | KDM4EALDH1A1MAPTHTR2AATM | |
| SCHEMBL605212 | 0.77 | HTR2A (0.61) | ALDH1A1MAPTHTR2AHTR1AHTR2C | |
| SCHEMBL7364107 | 0.75 | TRPM4 (0.43) | ALDH1A1MAPTHTR2APOLBRAD52 | |
| SCHEMBL2311037 | 0.75 | TRPM4 (0.48) | KDM4EALDH1A1MAPTHTR2AMEN1 | |
| SCHEMBL7247940 | 0.75 | DHODH (0.49) | ALDH1A1MAPTHTR2AHTR2CPOLB | |
| SCHEMBL7249959 | 0.75 | L3MBTL1 (0.47) | ALDH1A1MAPTHTR2APOLBRAD52 | |
| SCHEMBL27622116 | 0.75 | TRPM4 (0.43) | ALDH1A1MAPTHTR2APOLBRAD52 | |
| SCHEMBL598643 | 0.74 | TRPM4 (0.46) | KDM4EALDH1A1MAPTHTR2AATM | |
| SCHEMBL6788451 | 0.74 | NCF1 (0.60) | HTR2AHTR1AHTR2CHTR2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030108892-A1 | Irradiation of pyrene and dimethyl aniline in water, forming labels for oligonucleotides, proteins, ceramics, transistors, semiconductors, insulators, or glass | THE UNIVERSITY OF MANCHESTER (GB) | 2003-06-12 | — | — | US | disclosed |
| EP-1242360-A2 | EXCIPLEXES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001046121-A2 | EXCIPLEXES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108892-A1 | Irradiation of pyrene and dimethyl aniline in water, forming labels for oligonucleotides, proteins, ceramics, transistors, semiconductors, insulators, or glass | MDM4, PHAX, DIMT1 | KDM4E 2365/4885ALDH1A1 4658/4885MAPT 1213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.