SCHEMBL725053

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL723931	0.90	TUBB1 (0.57)	PDGFRBEGFRTUBB1TUBB4ATUBB
	SCHEMBL724651	0.90	TUBB4A (0.49)	EGFRTUBB1TUBB4ATUBBTUBA3C
	SCHEMBL724236	0.89	TUBB4A (0.56)	EGFRTUBB1TUBB4ATUBBTUBA3C
	SCHEMBL4422699	0.89	TUBB4A (0.50)	EGFRTUBB1TUBB4ATUBBTUBA3C
	SCHEMBL3469479	0.89	EGFR (0.47)	PDGFRBEGFRTUBB1TUBB4ATUBB
	SCHEMBL723964	0.89	TUBB4A (0.51)	EGFRTUBB1TUBB4ATUBBTUBA3C
	SCHEMBL724356	0.89	PDGFRB (0.49)	PDGFRBKDREGFRTUBB1TUBB4A
	SCHEMBL725347	0.89	TUBB4A (0.56)	TUBB1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL723242	0.89	EGFR (0.50)	EGFRTUBB1TUBB4ATUBBTUBA3C
	SCHEMBL4418868	0.88	EGFR (0.47)	PDGFRBEGFRTUBB1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.