Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62885 | 0.76 | NPSR1 (0.50) | USP2CYP1A2ALDH1A1KDM4EKMT2A | |
| SCHEMBL7252333 | 0.70 | SMN1; SMN2 (0.45) | USP2CYP1A2ALDH1A1KDM4EKMT2A | |
| SCHEMBL13118482 | 0.65 | MEN1 (0.36) | USP2CYP1A2ALDH1A1KDM4EKMT2A | |
| SCHEMBL12364192 | 0.64 | L3MBTL1 (0.46) | CYP1A2ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL24761226 | 0.63 | CYP1A2 (0.42) | CYP1A2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1917991 | 0.63 | CYP1A2 (0.42) | CYP1A2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1224786 | 0.63 | TYMP (0.45) | USP2CYP1A2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13272912 | 0.63 | CYP1A2 (0.42) | USP2CYP1A2ALDH1A1KDM4EKMT2A | |
| SCHEMBL21886927 | 0.63 | THRB (0.60) | CYP1A2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL31330663 | 0.63 | KDM4C (0.51) | USP2CYP1A2ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030100549-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) | VERTEX PHARMACEUTICALS INCORPORATED | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100549-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) | MAP3K1, JUN, MAP3K7 | USP2 1312/4885CYP1A2 4619/4885ALDH1A1 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.