Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7244666 | 0.79 | MAPT (0.39) | LGALS8LGALS3NOD2NOD1F10 | |
| SCHEMBL7247626 | 0.78 | CCR2 (0.46) | MCL1F10SRD5A2LTB4RLTB4R2 | |
| SCHEMBL7244670 | 0.76 | MAPT (0.36) | MCL1LGALS8LGALS3NOD2NOD1 | |
| SCHEMBL7700461 | 0.76 | PLA2G4A (0.47) | NOD2NOD1MAOAKDM4ECRHBP | |
| SCHEMBL7246843 | 0.75 | KDM4E (0.41) | NOD2NOD1F10MAOAKDM4E | |
| SCHEMBL7247084 | 0.74 | KDM4E (0.47) | NOD2NOD1F10KDM4ECRHBP | |
| SCHEMBL2969223 | 0.67 | SRD5A2 (0.57) | F10MAOAKDM4ECRHBPCRHR2 | |
| SCHEMBL18733284 | 0.67 | LTB4R (0.63) | F10SRD5A2LTB4RLTB4R2MEN1 | |
| SCHEMBL2016346 | 0.67 | SRD5A2 (0.56) | F10MAOAKDM4ECRHBPCRHR2 | |
| SCHEMBL31159349 | 0.66 | NOD2 (0.61) | MCL1NOD2NOD1F10MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670388-B1 | Fatty acid synthase inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-12-30 | — | — | US | disclosed |
| WO-2002000620-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-01-03 | — | — | WO | disclosed |