Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307747 | 0.84 | PSMB8 (0.53) | PSMB8ADORA1ADORA3MAOBADORA2A | |
| SCHEMBL1918622 | 0.82 | DDAH1 (0.53) | PSMB8ADORA1ADORA3MAOBADORA2A | |
| SCHEMBL5738314 | 0.82 | PSMB8 (0.51) | PSMB8ADORA1ADORA3MAOBADORA2A | |
| SCHEMBL1917492 | 0.79 | PSMB8 (0.49) | PSMB8ADORA1ADORA3MAOBADORA2A | |
| SCHEMBL11574137 | 0.78 | PSMB8 (0.59) | PSMB8ADORA1ADORA3MAOBADORA2A | |
| SCHEMBL1917800 | 0.78 | PSMB8 (0.47) | PSMB8 | |
| SCHEMBL38661181 | 0.77 | ADORA1 (0.51) | PSMB8ADORA1ADORA3MAOBADORA2A | |
| SCHEMBL7608595 | 0.76 | PSMB8 (0.45) | PSMB8ADORA1ADORA3MAOBADORA2A | |
| SCHEMBL2845899 | 0.76 | POLB (0.46) | PSMB8ADORA1ADORA3MAOBADORA2A | |
| SCHEMBL66295 | 0.75 | PSMB8 (0.59) | PSMB8ADORA1ADORA3MAOBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030013724-A1 | Novel prolines as antimicrobial agents | HAMMOND MILTON L (US) | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013724-A1 | Novel prolines as antimicrobial agents | AARS1, EPRS1, TRMT1 | PSMB8 1867/4885ADORA1 2185/4885ADORA3 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.