Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889469 | 0.82 | RPS6KA2 (0.41) | RPS6KA2ALDH1A1MEN1KMT2A | |
| SCHEMBL7253013 | 0.81 | ADRA1A (0.35) | RPS6KA2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL6491631 | 0.80 | LMNA (0.36) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL6502640 | 0.70 | MEN1 (0.35) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL5889654 | 0.69 | ITGB3 (0.37) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL6491374 | 0.65 | HRAS (0.37) | — | |
| SCHEMBL4032771 | 0.64 | MAOB (0.49) | — | |
| SCHEMBL5889470 | 0.63 | RPS6KA2 (0.42) | RPS6KA2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7252709 | 0.62 | TERT (0.40) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL7253018 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000650-A9 | NOVEL COMPOUNDS POSSESSING ANTIBACTERIAL, ANTIFUNGAL OR ANTITUMOR ACTIVITY | GENELABS TECH INC (US) | 2003-03-06 | — | — | WO | disclosed |