Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 9/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253017 | 0.81 | RPS6KA2 (0.33) | ADRA1AADRA1DADRA1BMEN1KMT2A | |
| SCHEMBL5889469 | 0.80 | RPS6KA2 (0.41) | MEN1KMT2AALDH1A1RPS6KA2 | |
| SCHEMBL7253018 | 0.78 | — | — | |
| SCHEMBL7252709 | 0.69 | TERT (0.40) | JAK2JAK1TYK2JAK3MEN1 | |
| SCHEMBL5891993 | 0.60 | MAOA (0.41) | ADRA1AADRA1DADRA1B | |
| SCHEMBL5889470 | 0.60 | RPS6KA2 (0.42) | MEN1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL6491631 | 0.59 | LMNA (0.36) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7542296 | 0.58 | ITGB3 (0.36) | — | |
| SCHEMBL5889536 | 0.58 | TERT (0.42) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7540448 | 0.58 | WDR5 (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000650-A9 | NOVEL COMPOUNDS POSSESSING ANTIBACTERIAL, ANTIFUNGAL OR ANTITUMOR ACTIVITY | GENELABS TECH INC (US) | 2003-03-06 | — | — | WO | disclosed |