Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804342 | 0.75 | ADAM17 (0.37) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7263114 | 0.74 | LMNA (0.36) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7253031 | 0.74 | FFAR1 (0.40) | KMT2ASLC6A3MEN1PPARD | |
| SCHEMBL1711724 | 0.72 | NPC1 (0.77) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL19002526 | 0.69 | POLB (0.42) | SMN1; SMN2SLC6A3MAPTPOLB | |
| SCHEMBL4721186 | 0.69 | L3MBTL1 (0.48) | RAB9ASMN1; SMN2L3MBTL1KMT2ASLC6A3 | |
| SCHEMBL5757765 | 0.68 | ACACB (0.41) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7253353 | 0.68 | MEN1 (0.39) | RAB9ASMN1; SMN2MAPK1KMT2AMAPT | |
| SCHEMBL3098479 | 0.68 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL21151 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610731-B2 | Antiinflammatory | BRISTOL-MYERS SQUIBB COMPANY | 2003-08-26 | — | — | US | disclosed |