Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154174 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8154422 | 0.75 | — | — | |
| SCHEMBL7263989 | 0.74 | KDM4E (0.44) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7257430 | 0.74 | NPC1 (0.43) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7258099 | 0.74 | — | — | |
| SCHEMBL7253779 | 0.73 | — | — | |
| SCHEMBL5940600 | 0.73 | — | — | |
| SCHEMBL8152565 | 0.72 | — | — | |
| SCHEMBL7263484 | 0.71 | KDM4E (0.41) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7259083 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003000665-A1 | ANTIBACTERIAL URACIL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |