Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321846 | 0.86 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2ALOX12CYP3A4ACHE | |
| SCHEMBL8600372 | 0.86 | LMNA (0.48) | LMNASMN1; SMN2ALOX12CYP3A4CYP1A2 | |
| SCHEMBL6649833 | 0.84 | ACHE (0.42) | LMNASMN1; SMN2ALOX12CYP3A4CYP1A2 | |
| SCHEMBL28205894 | 0.81 | ALDH1A1 (0.47) | LMNASMN1; SMN2ALOX12CYP3A4CYP1A2 | |
| SCHEMBL17145136 | 0.80 | LMNA (0.49) | LMNASMN1; SMN2ALOX12CYP3A4CYP1A2 | |
| SCHEMBL27443458 | 0.79 | LMNA (0.44) | LMNASMN1; SMN2ALOX12CYP3A4CYP1A2 | |
| SCHEMBL15503798 | 0.76 | LMNA (0.59) | LMNASMN1; SMN2ALOX12CYP3A4CYP1A2 | |
| SCHEMBL8596689 | 0.75 | TLR8 (0.61) | LMNASMN1; SMN2TLR8ALDH1A1GAA | |
| SCHEMBL3953291 | 0.75 | KDM4E (0.52) | LMNASMN1; SMN2CYP3A4ACHEALDH1A1 | |
| SCHEMBL29508392 | 0.75 | LMNA (0.40) | LMNASMN1; SMN2ALOX12CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212270-A1 | Process for preparing 1-Substituted, 2-Substituted 1-H-Imidazo(4,5-c)quinolin-4-Amines | 3M INNOVATIVE PROPERTIES COMPANY | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212270-A1 | Process for preparing 1-Substituted, 2-Substituted 1-H-Imidazo(4,5-c)quinolin-4-Amines | IFNAR1, IRF3, IFNG | LMNA 2048/4885SMN1; SMN2 3550/4885ALOX12 3567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.