Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250882 | 0.88 | HPGD (0.39) | KDM4ENPC1RAB9AALDH1A1KCNMA1 | |
| SCHEMBL7250888 | 0.81 | SMN1; SMN2 (0.44) | MAPK1KDM4ENPC1THRBRAB9A | |
| SCHEMBL7254543 | 0.77 | RECQL (0.47) | KDM4ERECQLALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7251136 | 0.76 | HTT (0.42) | KDM4EALDH1A1KCNMA1SMN1; SMN2KMT2A | |
| SCHEMBL7251048 | 0.75 | KDM4E (0.45) | MAPK1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL7587241 | 0.74 | KDM4E (0.40) | MAPK1KDM4ENPC1MITFTHRB | |
| SCHEMBL7256864 | 0.72 | L3MBTL1 (0.46) | KDM4ERECQLALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL4668106 | 0.71 | ALDH1A1 (0.43) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL4667405 | 0.71 | TAS1R3 (0.41) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL7251829 | 0.70 | HPGD (0.43) | KDM4ENPC1RAB9AALDH1A1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635091-B2 | Oxidation color dye and coupler | L'OREAL S. A. (FR) | 2003-10-21 | — | — | US | disclosed |
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | KRT18, FH, FGB | MAPK1 2709/4885KDM4E 868/4885NPC1 4448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.