Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17361195 | 1.00 | RAB9A (0.54) | RAB9AHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL17361189 | 1.00 | RAB9A (0.54) | RAB9AHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4633628 | 0.94 | RAB9A (0.49) | RAB9AHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5935761 | 0.94 | RAB9A (0.49) | RAB9AHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL17361182 | 0.90 | ALDH1A1 (0.52) | RAB9AHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL17361180 | 0.90 | ALDH1A1 (0.52) | RAB9AHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL17361197 | 0.90 | ALDH1A1 (0.52) | RAB9AHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL11754448 | 0.83 | HPGD (0.40) | RAB9AHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8627456 | 0.82 | HPGD (0.50) | RAB9AHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1813924 | 0.82 | HPGD (0.50) | RAB9AHSD17B10ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105219527-B | Tetrahydrofuran derivatives as fragrances | 西姆莱斯股份公司 | 2023-11-14 | — | — | CN | claimed |
| US-10344247-B2 | Tetrahydrofuran derivatives as fragrances | SYMRISE AG (DE) | 2019-07-09 | — | — | US | claimed |
| EP-2960235-B1 | TETRAHYDROFURAN DERIVATIVES AS FRAGRANCES | SYMRISE AG (DE) | 2018-09-26 | — | — | EP | claimed |
| US-20150376546-A1 | TETRAHYDROFURAN DERIVATIVES AS FRAGRANCES | SYMRISE AG (DE) | 2015-12-31 | — | — | US | claimed |
| CN-105219527-B | Tetrahydrofuran derivatives as fragrances | 西姆莱斯股份公司 | 2023-11-14 | — | — | CN | disclosed |
| US-10344247-B2 | Tetrahydrofuran derivatives as fragrances | SYMRISE AG (DE) | 2019-07-09 | — | — | US | disclosed |
| US-10344247-B2 | Tetrahydrofuran derivatives as fragrances | SYMRISE AG (DE) | 2019-07-09 | — | — | US | disclosed |
| US-20150376546-A1 | TETRAHYDROFURAN DERIVATIVES AS FRAGRANCES | SYMRISE AG (DE) | 2015-12-31 | — | — | US | disclosed |
| US-20150376546-A1 | TETRAHYDROFURAN DERIVATIVES AS FRAGRANCES | SYMRISE AG (DE) | 2015-12-31 | — | — | US | disclosed |
| US-20150376546-A1 | TETRAHYDROFURAN DERIVATIVES AS FRAGRANCES | SYMRISE AG (DE) | 2015-12-31 | — | — | US | disclosed |
| EP-2960235-A1 | Tetrahydrofuran derivatives as fragrances | Symrise AG (DE) | 2015-12-30 | — | — | EP | disclosed |
| WO-2003014106-A1 | METHOD FOR PREPARING OPTICALLY ACTIVE α-SUBSTITUTED HETEROCYCLICCARBOXYLIC ACID ESTER | GENOFOCUS CO., LTD. (KR) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376546-A1 | TETRAHYDROFURAN DERIVATIVES AS FRAGRANCES | TRPA1, ADH5, SORD | RAB9A 4585/4885HSD17B10 167/4885ALDH1A1 29/4885 |
| US-10344247-B2 | Tetrahydrofuran derivatives as fragrances | TRPA1, ADH5, SORD | RAB9A 4585/4885HSD17B10 167/4885ALDH1A1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.