Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.44 |
| ▸ | WEE1 | P30291 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599470 | 0.74 | POLB (0.41) | — | |
| SCHEMBL27782044 | 0.74 | CA1 (0.42) | SLC6A4SLC6A3SLC6A2MAPKAPK2 | |
| SCHEMBL7258181 | 0.70 | ADRB1 (0.43) | ADRB1SLC6A4SLC6A3SLC6A2L3MBTL1 | |
| SCHEMBL5474914 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL3643745 | 0.68 | CHRNA7 (0.42) | — | |
| SCHEMBL3644041 | 0.67 | FAAH (0.42) | — | |
| SCHEMBL2453349 | 0.65 | FAAH (0.38) | — | |
| SCHEMBL9596252 | 0.65 | ADRB1 (1.00) | ADRB1SLC6A4SLC6A3SLC6A2HTR6 | |
| SCHEMBL5787094 | 0.64 | ADORA2A (0.34) | — | |
| SCHEMBL9593901 | 0.63 | ADRB1 (1.00) | ADRB1SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |