Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683759 | 0.87 | ADRB1 (0.56) | ADRB1SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL11076879 | 0.80 | HTR3E (0.41) | ADRB1 | |
| SCHEMBL21382496 | 0.74 | SLC6A2 (0.34) | ADRB1SLC6A2SLC6A4SLC6A3MMP1 | |
| SCHEMBL23244311 | 0.72 | PKM (0.42) | SLC6A4SLC6A3 | |
| SCHEMBL7258296 | 0.70 | ADRB1 (0.48) | ADRB1SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL846305 | 0.69 | NPC1 (0.53) | — | |
| SCHEMBL9052450 | 0.67 | MMP1 (0.34) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL28295939 | 0.66 | MAPT (0.50) | SLC6A2SLC6A4SLC6A3GFERL3MBTL1 | |
| SCHEMBL1811425 | 0.66 | SLC6A2 (0.37) | ADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7262930 | 0.65 | HTR2C (0.44) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |