Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NADK | O95544 | 1/20 | 0.51 |
| ▸ | TRPM2 | O94759 | 5/20 | 0.49 |
| ▸ | SLC28A2 | O43868 | 5/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254210 | 0.94 | TRPM2 (0.47) | SIRT2SIRT1GAPDHHSD17B10NADK | |
| SCHEMBL1097330 | 0.88 | SIRT2 (0.58) | SIRT2SIRT1GAPDHHSD17B10NADK | |
| SCHEMBL1097331 | 0.88 | SIRT2 (0.58) | SIRT2SIRT1GAPDHHSD17B10NADK | |
| SCHEMBL1098546 | 0.86 | GAPDH (0.55) | SIRT2SIRT1GAPDHHSD17B10NADK | |
| SCHEMBL7257500 | 0.84 | ALDH1A1 (0.53) | NADKADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7257437 | 0.81 | PRKAB2 (0.39) | SIRT2SIRT1GAPDHHSD17B10TRPM2 | |
| SCHEMBL1097695 | 0.79 | GAPDH (0.46) | SIRT2SIRT1GAPDHHSD17B10NADK | |
| SCHEMBL11417135 | 0.78 | P2RX3 (0.52) | GAPDHTRPM2SLC28A2ADORA3ADORA2A | |
| SCHEMBL1098133 | 0.78 | GAPDH (0.45) | SIRT2SIRT1GAPDHHSD17B10NADK | |
| SCHEMBL1097068 | 0.78 | ALDH1A1 (0.47) | SIRT2SIRT1GAPDHHSD17B10NADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051881-A1 | SUBSTITUTED PURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS BY SOLID-PHASE COMBINATORIAL STRATEGIES | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |