Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259490 | 0.91 | CNR1 (0.39) | ROCK2ACACBACACASLC5A1NPC1 | |
| SCHEMBL7263737 | 0.89 | AVPR1B (0.41) | SLC5A1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL7258980 | 0.89 | FAAH (0.42) | ROCK2FAAHCHEK1CHEK2NPC1 | |
| SCHEMBL7264336 | 0.88 | FAAH (0.34) | ROCK2ACACBACACAFAAHCHEK1 | |
| SCHEMBL7259234 | 0.87 | FFAR4 (0.41) | ROCK2ACACBACACASLC5A1NPC1 | |
| SCHEMBL7263079 | 0.87 | TP53 (0.46) | ROCK2NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL7259217 | 0.86 | SMN1; SMN2 (0.41) | ROCK2ACACBACACANPC1TP53 | |
| SCHEMBL7259376 | 0.86 | MRGPRX4 (0.39) | ROCK2ACACBACACASLC5A1NPC1 | |
| SCHEMBL7263757 | 0.85 | HDAC1 (0.40) | SLC5A1 | |
| SCHEMBL7258877 | 0.82 | SMN1; SMN2 (0.40) | ROCK2NPC1TP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |