Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258783 | 0.88 | ROCK2 (0.37) | FAAHROCK2MAP4K4ACACBACACA | |
| SCHEMBL7258928 | 0.86 | SMN1; SMN2 (0.34) | SMN1; SMN2TP53NPC1RAB9ASLC5A1 | |
| SCHEMBL7259390 | 0.85 | RAB9A (0.38) | SMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL7264021 | 0.84 | FFAR1 (0.35) | SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL7259504 | 0.84 | MCHR1 (0.38) | SMN1; SMN2NPC1MAPTHDAC6 | |
| SCHEMBL7264648 | 0.82 | BCHE (0.38) | SMN1; SMN2TP53NPC1RAB9AHDAC6 | |
| SCHEMBL7259442 | 0.81 | MAPT (0.42) | SMN1; SMN2TP53NPC1RAB9AMAPT | |
| SCHEMBL7259380 | 0.81 | SMN1; SMN2 (0.39) | ROCK2SMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL7264002 | 0.81 | NPC1 (0.37) | NPC1RAB9AMAPT | |
| SCHEMBL7259490 | 0.80 | CNR1 (0.39) | ROCK2ACACBACACASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |