Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | PRKX | P51817 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.37 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263737 | 0.94 | AVPR1B (0.41) | CNR1MMENPC1TP53RAB9A | |
| SCHEMBL7259234 | 0.93 | FFAR4 (0.41) | CNR1ACACBACACAROCK1ROCK2 | |
| SCHEMBL7259376 | 0.92 | MRGPRX4 (0.39) | ACACBACACAROCK1ROCK2DYRK3 | |
| SCHEMBL7259217 | 0.92 | SMN1; SMN2 (0.41) | ACACBACACAROCK1ROCK2UTS2R | |
| SCHEMBL7258783 | 0.91 | ROCK2 (0.37) | CNR1ACACBACACAROCK1ROCK2 | |
| SCHEMBL7263079 | 0.90 | TP53 (0.46) | ROCK1ROCK2NPC1TP53RAB9A | |
| SCHEMBL7263757 | 0.88 | HDAC1 (0.40) | HTTSLC5A1 | |
| SCHEMBL7258980 | 0.87 | FAAH (0.42) | ROCK1ROCK2NPC1TP53RAB9A | |
| SCHEMBL7258877 | 0.85 | SMN1; SMN2 (0.40) | ROCK1ROCK2CDK2NPC1TP53 | |
| SCHEMBL7258741 | 0.85 | HSD17B1 (0.38) | CNR1ACACBACACAROCK1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |