Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28408131 | 0.88 | ADRB1 (0.43) | ADRB1SIRT6ALDH1A1LMNADPP4 | |
| SCHEMBL7230204 | 0.87 | ADRB1 (0.44) | ADRB1SIRT6ALDH1A1KCNJ1KCNH2 | |
| SCHEMBL30165832 | 0.81 | ALDH1A1 (0.50) | ADRB1SIRT6ALDH1A1LMNAKDM4E | |
| SCHEMBL13860379 | 0.81 | DPP4 (0.43) | DPP4DPP7 | |
| SCHEMBL794507 | 0.81 | DPP4 (0.43) | ADRB1DPP4DPP7 | |
| SCHEMBL2386164 | 0.80 | DPP4 (0.47) | DPP4DPP7SLC18A3 | |
| Hydrochloric Acid SCHEMBL28773228 | 0.79 | DPP4 (0.46) | DPP4DPP7SLC18A3 | |
| SCHEMBL1720843 | 0.78 | NSD2 (0.44) | DPP4DPP7KCNH2 | |
| SCHEMBL1184197 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL522461 | 0.78 | ADRB1 (0.43) | ADRB1SIRT6ALDH1A1DPP4KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | disclosed |