Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725920 | 0.96 | LMNA (0.33) | LMNAHTTMLYCDCYP1A2TSHR | |
| SCHEMBL725918 | 0.95 | MLYCD (0.33) | LMNAHTTMLYCDCYP1A2TSHR | |
| SCHEMBL727274 | 0.79 | MLYCD (0.39) | MLYCD | |
| SCHEMBL726029 | 0.76 | MLYCD (0.37) | LMNAHTTMLYCDSMN1; SMN2 | |
| SCHEMBL725494 | 0.75 | ALDH1A1 (0.38) | LMNAHTTTSHRSMN1; SMN2 | |
| SCHEMBL727294 | 0.74 | ALDH1A1 (0.53) | TSHRSMN1; SMN2 | |
| SCHEMBL727459 | 0.72 | GSR (0.46) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL725495 | 0.71 | ALDH1A1 (0.40) | LMNAHTTTSHRSMN1; SMN2 | |
| SCHEMBL9681297 | 0.70 | CES2 (0.48) | LMNA | |
| SCHEMBL10947586 | 0.70 | HPGD (0.44) | LMNAHTTMLYCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585431-B1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2017-09-06 | — | — | EP | disclosed |
| US-9657435-B2 | Metal free bleaching composition | BASF SE (DE) | 2017-05-23 | — | — | US | disclosed |
| US-20130117941-A1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
| EP-2585431-A1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2013-05-01 | — | — | EP | disclosed |
| WO-2012000846-A1 | METAL FREE BLEACHING COMPOSITION | BASF SE (DE) | 2012-01-05 | — | — | WO | disclosed |