Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679513 | 0.86 | HDAC3 (0.48) | CES2CES1MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL9681281 | 0.84 | CA1 (0.47) | CES2CES1MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL10947586 | 0.82 | HPGD (0.44) | ALDH1A1LMNAMAPTELANERAB9A | |
| SCHEMBL10385926 | 0.81 | TSHR (0.52) | CES2CES1MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL57578 | 0.81 | CES2 (0.53) | CES2CES1MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL10458476 | 0.81 | CES2 (0.53) | CES2CES1MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL10103988 | 0.81 | CA2 (0.46) | CES2CES1ALDH1A1LMNATDP1 | |
| SCHEMBL10384361 | 0.79 | MLYCD (0.45) | CES2CES1ALDH1A1LMNACA1 | |
| SCHEMBL58072 | 0.79 | CES1 (0.45) | CES2CES1ALDH1A1MAPT | |
| SCHEMBL22745248 | 0.78 | PDK2 (0.34) | ALDH1A1LMNAHDAC1PLK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |