Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7255797 | 0.78 | CTSS (0.47) | CTSKLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6206920 | 0.76 | CTSS (0.41) | LMNAHTTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7255683 | 0.74 | LMNA (0.36) | MTNR1AMTNR1BLMNAHTTSMN1; SMN2 | |
| SCHEMBL7259162 | 0.74 | ALDH1A1 (0.40) | MTNR1AMTNR1BPTPN2PTPN1ALDH1A1 | |
| SCHEMBL6630426 | 0.73 | CTSC (0.47) | — | |
| SCHEMBL7260207 | 0.72 | PTGER4 (0.43) | CTSK | |
| SCHEMBL6633248 | 0.72 | LMNA (0.35) | MTNR1AMTNR1BLMNAHTTSMN1; SMN2 | |
| SCHEMBL6632745 | 0.72 | ALDH1A1 (0.39) | PTPN2PTPN1ALDH1A1 | |
| SCHEMBL6632750 | 0.72 | ALDH1A1 (0.39) | PTPN2PTPN1ALDH1A1 | |
| SCHEMBL6630204 | 0.72 | ALDH1A1 (0.39) | PTPN2PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000838-A1 | PEPTIDIC COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-31 | — | — | WO | disclosed |