Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259783 | 0.88 | MAPKAPK2 (0.39) | MAPKAPK2 | |
| SCHEMBL7256246 | 0.87 | LMNA (0.40) | POLBALDH1A1CYP3A4TDP1MEN1 | |
| SCHEMBL7259827 | 0.86 | TSHR (0.44) | MAPKAPK2ALDH1A1TDP1MEN1NPC1 | |
| SCHEMBL7255145 | 0.86 | NR1H4 (0.41) | MAPKAPK2ALDH1A1KMT2A | |
| SCHEMBL7255070 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TDP1NPC1RAB9AKMT2A | |
| SCHEMBL7255149 | 0.79 | NR1H4 (0.36) | MAPKAPK2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL7256248 | 0.78 | LMNA (0.40) | ALDH1A1CYP1A2CYP3A4CYP2C9NPSR1 | |
| SCHEMBL7256009 | 0.74 | NPC1 (0.38) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7259830 | 0.73 | MAPKAPK2 (0.38) | MAPKAPK2ALDH1A1NPC1RAB9A | |
| SCHEMBL7260764 | 0.69 | ALDH1A1 (0.43) | MAPKAPK2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | claimed |