Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255070 | 0.93 | ALDH1A1 (0.40) | NR1H4GCGRPDE7BALDH1A1CNR2 | |
| SCHEMBL7256248 | 0.88 | LMNA (0.40) | NR1H4GCGRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7259783 | 0.87 | MAPKAPK2 (0.39) | NR1H4MAPKAPK2GCGRSMN1; SMN2LMNA | |
| SCHEMBL7255145 | 0.87 | NR1H4 (0.41) | NR1H4MAPKAPK2GCGRALDH1A1KDM4E | |
| SCHEMBL7256009 | 0.80 | NPC1 (0.38) | NR1H4ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL7256246 | 0.80 | LMNA (0.40) | GCGRALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL7259782 | 0.79 | POLB (0.39) | MAPKAPK2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL7260764 | 0.78 | ALDH1A1 (0.43) | MAPKAPK2ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL7255167 | 0.76 | LTB4R2 (0.44) | ALDH1A1KDM4ESMN1; SMN2NPC1GLA | |
| SCHEMBL7259830 | 0.72 | MAPKAPK2 (0.38) | MAPKAPK2ALDH1A1KDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | claimed |