Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255070 | 0.90 | ALDH1A1 (0.40) | LMNASMN1; SMN2NR1H4GCGR | |
| SCHEMBL7259782 | 0.88 | POLB (0.39) | MAPKAPK2 | |
| SCHEMBL7255149 | 0.87 | NR1H4 (0.36) | MAPKAPK2LMNASMN1; SMN2NR1H4GCGR | |
| SCHEMBL7256248 | 0.87 | LMNA (0.40) | LMNASMN1; SMN2NR1H4GCGR | |
| SCHEMBL7259830 | 0.86 | MAPKAPK2 (0.38) | MAPKAPK2SMN1; SMN2GPR88 | |
| SCHEMBL7255145 | 0.79 | NR1H4 (0.41) | MAPKAPK2LMNANR1H4GCGR | |
| SCHEMBL7256009 | 0.78 | NPC1 (0.38) | LMNASMN1; SMN2NR1H4 | |
| SCHEMBL7256246 | 0.78 | LMNA (0.40) | LMNASMN1; SMN2GCGR | |
| SCHEMBL7260764 | 0.76 | ALDH1A1 (0.43) | MAPKAPK2SMN1; SMN2 | |
| SCHEMBL7255167 | 0.74 | LTB4R2 (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | claimed |