Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255070 | 0.93 | ALDH1A1 (0.40) | LMNAKDM4EALDH1A1TDP1NPC1 | |
| SCHEMBL7255149 | 0.88 | NR1H4 (0.36) | LMNAKDM4EALDH1A1TDP1NPC1 | |
| SCHEMBL7259783 | 0.87 | MAPKAPK2 (0.39) | LMNASMN1; SMN2NR1H4GCGR | |
| SCHEMBL7256246 | 0.87 | LMNA (0.40) | LMNAMAPK1KDM4EALDH1A1TDP1 | |
| SCHEMBL7256009 | 0.82 | NPC1 (0.38) | LMNAMAPK1KDM4EALDH1A1NPC1 | |
| SCHEMBL7255145 | 0.80 | NR1H4 (0.41) | LMNAKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL7260764 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1NPC1HPGDPKM | |
| SCHEMBL7259782 | 0.78 | POLB (0.39) | ALDH1A1TDP1NPC1CYP3A4MEN1 | |
| SCHEMBL7255167 | 0.76 | LTB4R2 (0.44) | KDM4EALDH1A1NPC1HPGDPKM | |
| SCHEMBL7259830 | 0.72 | MAPKAPK2 (0.38) | KDM4EALDH1A1NPC1HPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | claimed |