Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.60 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725005 | 0.82 | RAB9A (0.75) | TP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15085468 | 0.79 | TP53 (0.77) | MAPTTP53TSHRKMT2AMEN1 | |
| SCHEMBL31066866 | 0.75 | TLR8 (0.68) | MAPTTP53TSHRKMT2AMEN1 | |
| SCHEMBL31066873 | 0.75 | TLR8 (0.68) | MAPTTP53TSHRKMT2AMEN1 | |
| SCHEMBL9197881 | 0.75 | AGTR1 (1.00) | AGTR1AGTR2 | |
| SCHEMBL540895 | 0.74 | TP53 (0.65) | AGTR1AGTR2MAPTTP53POLB | |
| SCHEMBL28283760 | 0.74 | ALDH1A1 (0.64) | MAPTTP53TSHRKMT2AMEN1 | |
| SCHEMBL28716632 | 0.74 | LMNA (0.67) | AGTR1AGTR2MAPTTP53POLB | |
| SCHEMBL29968953 | 0.74 | LMNA (0.67) | AGTR1AGTR2MAPTTP53POLB | |
| SCHEMBL29968482 | 0.74 | LMNA (0.67) | AGTR1AGTR2MAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024937-A1 | BENZIMIDAZOLYLALKOXYARYL ALKANOIC ACID DERIVATIVES AND THEIR USE AS ANTIHYPERGLYCEMICS | MERCK PATENT GMBH (DE) | 2003-03-27 | — | — | WO | disclosed |