Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 2/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | PPIG | Q13427 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 4/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17460412 | 0.88 | ALDH1A1 (0.56) | LMNACYP1A2PPIDALDH1A1RECQL | |
| SCHEMBL2987840 | 0.84 | PTPN1 (0.42) | LMNACYP1A2CYP3A4MAOAPPID | |
| SCHEMBL8018845 | 0.83 | ALDH1A1 (0.43) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL7266498 | 0.82 | ALDH1A1 (0.46) | LMNACYP1A2ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL7435532 | 0.81 | ALDH1A1 (0.59) | LMNAPPIDALDH1A1RECQLMMP8 | |
| SCHEMBL2370973 | 0.78 | MMP8 (0.59) | LMNACYP1A2CYP3A4MAOAPPID | |
| SCHEMBL4419400 | 0.77 | ALDH1A1 (0.62) | LMNAPPIDALDH1A1RECQLMMP8 | |
| SCHEMBL1522684 | 0.77 | ALDH1A1 (0.58) | LMNACYP1A2PPIDALDH1A1RECQL | |
| SCHEMBL27385611 | 0.77 | PTPN1 (0.56) | CYP3A4ALDH1A1RECQLMMP8PTPN1 | |
| SCHEMBL3629075 | 0.76 | LMNA (0.50) | LMNACYP1A2CYP3A4MAOAPPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534513-B1 | Antiinflammatory agents and fibronectins | CELLTECH R&D LIMITED (GB) | 2003-03-18 | — | — | US | disclosed |