Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17460412 | 0.86 | ALDH1A1 (0.56) | ALDH1A1RECQLMMP8SMN1; SMN2MEN1 | |
| SCHEMBL7260552 | 0.83 | LMNA (0.46) | ALDH1A1RECQLMMP8SMN1; SMN2MEN1 | |
| SCHEMBL7435532 | 0.79 | ALDH1A1 (0.59) | ALDH1A1RECQLMMP8SMN1; SMN2TSHR | |
| SCHEMBL29256551 | 0.77 | ALDH1A1 (0.54) | ALDH1A1RECQLMMP8SMN1; SMN2PIN1 | |
| SCHEMBL4419400 | 0.76 | ALDH1A1 (0.62) | ALDH1A1RECQLMMP8SMN1; SMN2TSHR | |
| SCHEMBL1522684 | 0.76 | ALDH1A1 (0.58) | ALDH1A1RECQLMMP8SMN1; SMN2MEN1 | |
| SCHEMBL27385611 | 0.76 | PTPN1 (0.56) | ALDH1A1RECQLMMP8SMN1; SMN2MEN1 | |
| SCHEMBL6774685 | 0.75 | ALDH1A1 (0.73) | ALDH1A1RECQLMMP8PPARAPPARG | |
| SCHEMBL13721608 | 0.74 | MMP8 (0.47) | ALDH1A1RECQLMMP8PPARAPPARG | |
| SCHEMBL6938826 | 0.74 | ALDH1A1 (0.47) | ALDH1A1RECQLMMP8SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6099625-A | Ink composition | ZENECA LIMITED (GB) | 2000-08-08 | — | — | US | disclosed |
| EP-0823927-A2 | INK COMPOSITION | ZENECA LIMITED (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034916-A2 | INK COMPOSITION | ZENECA LIMITED (GB) | 1996-11-07 | — | — | WO | disclosed |