Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532023 | 0.87 | EGFR (0.48) | EGFRALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7257558 | 0.87 | TSPO (0.45) | EGFRALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7262276 | 0.84 | PDE4B (0.51) | EGFRALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7257548 | 0.83 | RAB9A (0.43) | EGFRALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7261259 | 0.82 | EGFR (0.48) | EGFRALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7536631 | 0.81 | CASP3 (0.47) | EGFRALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7260717 | 0.78 | ALDH1A1 (0.48) | EGFRALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7256749 | 0.78 | ALDH1A1 (0.48) | EGFRALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7261248 | 0.77 | ALDH1A1 (0.46) | EGFRALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7257604 | 0.77 | ALDH1A1 (0.46) | EGFRALDH1A1KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645983-B1 | Heterocyclic imines such as 3-(4-methoxyphenyl)-1,4-dihydro-4 -quinolinone, used as anticarcinogenic agents having cytolysis efficiency; side effect reduction | LABORATOIRE L. LAFON (FR) | 2003-11-11 | — | — | US | disclosed |