Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261140 | 0.94 | POLB (0.31) | SMN1; SMN2POLB | |
| SCHEMBL25440282 | 0.78 | HSD11B1 (0.31) | ALDH1A1HSD11B1 | |
| SCHEMBL7261167 | 0.78 | ATM (0.33) | ALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL9710092 | 0.77 | HTT (0.32) | — | |
| SCHEMBL17629524 | 0.76 | CHRNB2 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2788345 | 0.76 | CHRNB2 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8589177 | 0.73 | — | — | |
| SCHEMBL7291405 | 0.72 | HPGD (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2550000 | 0.72 | HSD11B1 (0.31) | ALDH1A1HSD11B1 | |
| SCHEMBL4016775 | 0.71 | SMN1; SMN2 (0.32) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000806-A1 | AMIDES OF CYCLIC AMINO ACIDS USED AS PDE 4 INHIBITORS | ELBION AG (DE) | 2003-12-31 | — | — | WO | claimed |
| WO-2004000806-A1 | AMIDES OF CYCLIC AMINO ACIDS USED AS PDE 4 INHIBITORS | ELBION AG (DE) | 2003-12-31 | — | — | WO | disclosed |