Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016775 | 0.94 | SMN1; SMN2 (0.32) | HTT | |
| SCHEMBL28340935 | 0.82 | ALDH1A1 (0.33) | HSD11B1ALDH1A1TSHR | |
| SCHEMBL112693 | 0.82 | ATM (0.32) | HSD11B1HPGD | |
| SCHEMBL17629524 | 0.78 | CHRNB2 (0.33) | HTTALDH1A1 | |
| SCHEMBL7260646 | 0.78 | ALDH1A1 (0.32) | HSD11B1ALDH1A1 | |
| SCHEMBL2788345 | 0.78 | CHRNB2 (0.33) | HTTALDH1A1 | |
| SCHEMBL8589177 | 0.75 | — | — | |
| SCHEMBL9710092 | 0.75 | HTT (0.32) | HTTHPGD | |
| SCHEMBL7291405 | 0.73 | HPGD (0.34) | ALDH1A1HPGD | |
| SCHEMBL2550000 | 0.73 | HSD11B1 (0.31) | HSD11B1HTTALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | LNPEP, LCLAT1, NPEPPS | HSD11B1 3514/4885HTT 4606/4885ALDH1A1 1559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.