Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412809 | 0.76 | CHRM2 (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL25440282 | 0.73 | HSD11B1 (0.31) | HSD11B1HTTALDH1A1TSHRHPGD | |
| SCHEMBL2522460 | 0.72 | L3MBTL1 (0.36) | HTTALDH1A1 | |
| SCHEMBL2788345 | 0.72 | CHRNB2 (0.33) | HTTALDH1A1 | |
| SCHEMBL7260646 | 0.72 | ALDH1A1 (0.32) | HSD11B1ALDH1A1 | |
| SCHEMBL17629524 | 0.72 | CHRNB2 (0.33) | HTTALDH1A1 | |
| SCHEMBL7261158 | 0.71 | THRB (0.39) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL7261874 | 0.70 | MIF (0.45) | ALDH1A1KMT2AHPGD | |
| SCHEMBL2928932 | 0.69 | ALDH1A1 (0.36) | HTTALDH1A1 | |
| SCHEMBL2928936 | 0.69 | ALDH1A1 (0.36) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556073-B1 | BICYCLIC PYRIDINYL PYRAZOLES | BAYER IP GMBH (DE) | 2014-07-23 | — | — | EP | disclosed |
| EP-2556073-A1 | BICYCLIC PYRIMIDINYL PYRAZOLES | Bayer Intellectual Property GmbH (DE) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011124539-A1 | BICYCLIC PYRIMIDINYL PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2011-10-13 | — | — | WO | disclosed |