Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265697 | 0.85 | ALDH1A1 (0.40) | L3MBTL1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL2053236 | 0.75 | AGTR1 (0.44) | L3MBTL1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9571283 | 0.73 | MAOB (0.52) | HTT | |
| SCHEMBL3005820 | 0.72 | ELANE (0.52) | L3MBTL1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8539617 | 0.71 | KCNN4 (0.44) | MEN1KMT2AALDH1A1TSHRLMNA | |
| Hydrogen Sulfide SCHEMBL27603601 | 0.70 | ELANE (0.50) | L3MBTL1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8056200 | 0.70 | ELANE (0.50) | L3MBTL1MEN1KMT2AALDH1A1PSMB5 | |
| SCHEMBL10433952 | 0.66 | ELANE (0.56) | L3MBTL1MEN1KMT2AALDH1A1TSHR | |
| Lithium SCHEMBL31260751 | 0.66 | ELANE (0.50) | L3MBTL1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL23706046 | 0.66 | PSMB5 (0.46) | L3MBTL1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003066626-A1 | DEUTERATED BIPHENYL-SUBSTITUTED BENZIMIDAZOLES AND MEDICAMENT CONTAINING SAID COMPOUNDS FOR THE TREATMENT OF HYPERTONIA | TURICUM DRUG DEVELOPMENT AG (CH) | 2003-08-14 | — | — | WO | disclosed |
| EP-0643709-A1 | 4-(1-$i(H)-PYRROL-1-YL)IMIDAZOLES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1995-03-22 | — | — | EP | disclosed |
| WO-1993000341-A1 | 4-(1-H-PYRROL-1-YL)IMIDAZOLES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1993-01-07 | — | — | WO | disclosed |