Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21198744 | 0.98 | NAAA (0.56) | NAAAEPHX1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL9538617 | 0.98 | NAAA (0.54) | NAAAEPHX1PKML3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21197531 | 0.96 | NAAA (0.53) | NAAAEPHX1PKML3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21197517 | 0.93 | L3MBTL1 (0.51) | NAAAEPHX1PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL16727370 | 0.84 | POLB (0.53) | NAAAPKML3MBTL1HSD17B10HSD11B1 | |
| SCHEMBL9795296 | 0.84 | HSD11B1 (0.49) | NAAAPKML3MBTL1HSD17B10HSD11B1 | |
| SCHEMBL7469332 | 0.82 | POLB (0.66) | NAAAEPHX1PKMSMN1; SMN2HSD17B10 | |
| SCHEMBL21860340 | 0.82 | HSD11B1 (0.51) | NAAAPKML3MBTL1HSD17B10HSD11B1 | |
| SCHEMBL19522182 | 0.82 | HSD11B1 (0.51) | NAAAPKML3MBTL1HSD17B10HSD11B1 | |
| SCHEMBL2485434 | 0.82 | L3MBTL1 (0.46) | NAAAPKML3MBTL1HSD17B10HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | claimed |